GeneGo

GeneGo - System Biology for Drug Discovery GeneGo develops tools for integration and systems level analysis of high-throughput experimental data in human biology and medicinal chemistry. One of their main products are MetaBase and MetaCore. The most comprehensive database in the field, MetaBase allows one to network over 90% of the known human proteins via physical protein-protein, protein-DNA and protein-compound interactions. MetaCore is an integrated software suite for functional analysis of microarrays, SAGE, proteomics and other experimental data. It is based on the unique, curated database of human protein-protein and protein-DNA interactions, transcriptional factors, signaling, metabolism and bioactive molecules. The analytical package includes intuitive tools for data visualization, mapping and exchange, multiple networking algorithms and in silico filters.

Citation: Nikolsky Y, Nikolskaya T, Bugrim A. (2005)Biological networks and analysis of experimental data in drug discovery. Drug Discov Today. 10(9):653-62. Review. PMID: 15894230